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Study of the association between serum levels of kynurenine and cardiovascular outcomes and overall mortality in chronic kidney disease.

Carolla El ChamiehIslam Amine LarabiNatalia Alencar de PinhoOriane LambertChristian CombeDenis FouqueLuc FrimatChristian JacquelinetMaurice LavilleSolène LavilleCéline LangeJean-Claude AlvarezZiad A MassySophie Liabeufnull null
Published in: Clinical kidney journal (2023)
Our findings imply that serum-free kynurenine, independently of other cardiovascular risk factors (including eGFR), is associated with fatal or nonfatal cardiovascular outcomes, particularly non-atheromatous cardiovascular events; in patients with CKD. Strategies to reduce serum kynurenine levels should be evaluated in further studies.
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