Stellate cells are in utero markers of pancreatic disease in cystic fibrosis.

Shih-Hsing LeirSvyatoslav TkachenkoAlekh ParanjapyeFrederick MecklerArnaud J Van WettereJenny L KerschnerElizabeth KuznetsovMakayla SchachtPulak GillurkarMisha RegouskiIuri Viotti PerisseCheyenne M MarriottYing LiuIan BundersonKenneth L WhiteIrina A Polejaeva Ann Harris

Published in: Molecular medicine (Cambridge, Mass.) (2024)

The transcriptomic changes and cellular imbalance that we observe likely have pivotal roles in the evolution of CF pancreatic disease and may provide therapeutic opportunities to delay or prevent pancreatic destruction in CF.

Keyphrases

cystic fibrosis
pseudomonas aeruginosa
induced apoptosis
lung function
rna seq
cell proliferation