One-Time Fecal Immunochemical Screening for Advanced Colorectal Neoplasia in Patients with CKD (DETECT Study).
Germaine WongRichard L HopeKirsten HowardJeremy R ChapmanAntoni CastellsSimon D RogerMichael J BourkePetra MacaskillRobin TurnerGabrielle WilliamsWai Hon LimCharmaine E LokFritz DiekmannNicholas B CrossShaundeep SenRichard D M AllenSteven J ChadbanCarol A PollockAllison TongArmando Teixeira-PintoJean Y H YangNarelle WilliamsEric Hoi Kit AuAnh KieuLaura JamesJonathan C CraigPublished in: Journal of the American Society of Nephrology : JASN (2019)
FIT appears to be an accurate screening test for patients with CKD, such that a negative test may rule out the diagnosis of colorectal cancer within 2 years. However, the risk of major complications from work-up colonoscopy are at least ten-fold higher than in the general population.