The Influence of ABCB1 (rs1045642 and rs4148738) Gene Polymorphisms on Rivaroxaban Pharmacokinetics in Patients Aged 80 Years and Older with Nonvalvular Atrial Fibrillation.
Dmitry Alekseevich SychevOlga Dmitrievna OstroumovaMarina S CherniaevaNataliia ShakhgildianKarin Badavievich MirzaevSherzod Pardaboevich AbdullaevNatalia P DenisenkoZhannet Alimovna SozaevaAnastasiya A KachanovaSvetlana GorbatenkovaVera ShastinaPublished in: High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension (2022)
ABCB1 (rs1045642 and rs4148738) polymorphisms didn't influence rivaroxaban pharmacokinetics in patients aged 80 years and older with NAF. TT carriers developed CRNMB more frequently compared with the CC rs1045642 and the CC and CT rs4148738 genotypes. The haplotype TT-TT haplotype was associated with a higher frequency of CRNMB.
Keyphrases
- magnetic resonance
- atrial fibrillation
- end stage renal disease
- newly diagnosed
- physical activity
- computed tomography
- prognostic factors
- peritoneal dialysis
- magnetic resonance imaging
- direct oral anticoagulants
- patient reported outcomes
- pet ct
- middle aged
- acute coronary syndrome
- left ventricular
- positron emission tomography
- patient reported
- image quality
- community dwelling