C60 fullerene and its nanocomplexes with anticancer drugs modulate circulating phagocyte functions and dramatically increase ROS generation in transformed monocytes.

Larysa M SkivkaSvitlana V PrylutskaMariia P RudykNataliia M KhranovskaIevgeniia V OpeidaVasyl V HurmachYuriy I PrylutskyyLeonid F SukhodubUwe Ritter

Published in: Cancer nanotechnology (2018)

The antineoplastic effect of C60 fullerene has been observed by direct toxic effect on tumor cells, as well as through the modulation of the functions of effector cells of antitumor immunity.

Keyphrases

induced apoptosis
dendritic cells
cell cycle arrest
cell death
solar cells
dna damage
regulatory t cells
endoplasmic reticulum stress
reactive oxygen species
signaling pathway
immune response
pi k akt
type iii