A Fe(III) intercalated clay nanoplatform for combined chemo/chemodynamic therapy.

Ying ChenJing ZhaiShiqi WeiAidong Tang Huaming Yang

Published in: Chemical communications (Cambridge, England) (2024)

A Fe(III) intercalated montmorillonite nanoplatform (Fe-MMT) was engineered for doxorubicin (DOX) loading. The constructed Fe-MMT/DOX nanoplatform could not only improve the production of H 2 O 2 to enhance chemodynamic therapy but interfere with DNA damage repair to amplify the efficacy of DOX, proving an ideal combination of chemotherapy and chemodynamic therapy.

Keyphrases

cancer therapy
photodynamic therapy
dna damage
drug delivery
stem cells
locally advanced
wastewater treatment
dna repair
mesenchymal stem cells
visible light