Treatment of symptomatic hyponatremia with hypertonic saline: a real-life observational study.
Irina ChifuAmelie GerstlBjörn LengenfelderDominik SchmittNils NaglerFassnacht MartinDirk WeismannPublished in: European journal of endocrinology (2021)
Sodium increase was more constant with hypertonic saline, but overcorrection rate was high, especially in severely symptomatic patients. Reducing bolus-volume and reevaluation before repeating bolus infusion might prevent overcorrection. Symptoms caused by hypovolemia can be misinterpreted as severely symptomatic hyponatremia and diuresis should be monitored.