Analysis of Polycyclic Aromatic Hydrocarbons in Ambient Aerosols by Using One-Dimensional and Comprehensive Two-Dimensional Gas Chromatography Combined with Mass Spectrometric Method: A Comparative Study.
Yoon Kyung AhnSo Hyeon JeonHyung Bae LimNa Rae ChoiGeum-Sook HwangYong Pyo KimJi-Yi LeePublished in: Journal of analytical methods in chemistry (2018)
Advanced separation technology paired with mass spectrometry is an ideal method for the analysis of atmospheric samples having complex chemical compositions. Due to the huge variety of both natural and anthropogenic sources of organic compounds, simultaneous quantification and identification of organic compounds in aerosol samples represents a demanding analytical challenge. In this regard, comprehensive two-dimensional gas chromatography with time-of-flight mass spectrometry (GC×GC-TOFMS) has become an effective analytical method. However, verification and validation approaches to quantify these analytes have not been critically evaluated. We compared the performance of gas chromatography with quadrupole mass spectrometry (GC-qMS) and GC×GC-TOFMS for quantitative analysis of eighteen target polycyclic aromatic hydrocarbons (PAHs). The quantitative obtained results such as limits of detection (LODs), limits of quantification (LOQs), and recoveries of target PAHs were approximately equivalent based on both analytical methods. Furthermore, a larger number of analytes were consistently identified from the aerosol samples by GC×GC-TOFMS compared to GC-qMS. Our findings suggest that GC×GC-TOFMS would be widely applicable to the atmospheric and related sciences with simultaneous target and nontarget analysis in a single run.
Keyphrases
- gas chromatography
- mass spectrometry
- liquid chromatography
- tandem mass spectrometry
- high resolution mass spectrometry
- gas chromatography mass spectrometry
- polycyclic aromatic hydrocarbons
- high performance liquid chromatography
- high resolution
- solid phase extraction
- simultaneous determination
- capillary electrophoresis
- particulate matter
- heavy metals
- water soluble
- real time pcr
- quantum dots