Chronic obstructive pulmonary disease upper airway microbiome is associated with select clinical characteristics.
Alexa A PragmanKatherine A KnutsonTrevor J GouldShane W HodgsonRichard E IsaacsonCavan S ReillyChris H WendtPublished in: PloS one (2019)
Among the upper airway microbiota of COPD subjects, anatomic site was associated with bacterial biomass, Shannon diversity, and β-diversity. ICS use and edentulous state were both associated with β-diversity. Age was associated with taxa relative abundance in oral and sputum samples, while FEV1pp was associated with taxa relative abundance in sputum samples only.