Broncho-Vaxom® (OM-85 BV) soluble components stimulate sinonasal innate immunity.
Vasiliki TriantafillouAlan D WorkmanNeil N PatelIvy W MainaCharles Ching Lick TongEdward Cheng-Lung KuanDavid W KennedyJames N PalmerNithin D AdappaSalomon Waizel-HaiatNoam A CohenPublished in: International forum of allergy & rhinology (2019)
OM-85 BV has ciliostimulatory and immunogenic properties that may be partially responsible for its observed efficacy as a respiratory therapeutic. These responses were NO-dependent and consistent with T2R activation. Further work is necessary to elucidate specific component-receptor signaling relationships.