The fusiform gyrus exhibits an epigenetic signature for Alzheimer's disease.

Dingailu MaIrfete S FetahuMei WangRui FangJiahui LiHang LiuTobin GramykIsabella IwanickiSophie GuWinnie XuLi TanFeizhen WuYujiang Geno Shi

Published in: Clinical epigenetics (2020)

This study identified a set of previously unexplored FUS-specific AD genes and their epigenetic characteristics, which may provide new insights into the molecular pathology of AD, attributing the genetic and epigenetic basis of FUS to AD development.

Keyphrases

dna methylation
genome wide
gene expression
cognitive decline
copy number
transcription factor
single molecule
bioinformatics analysis