AMBN mutations causing hypoplastic amelogenesis imperfecta and Ambn knockout-NLS-lacZ knockin mice exhibiting failed amelogenesis and Ambn tissue-specificity.

Tian LiangYuanyuan HuCharles E SmithAmelia S RichardsonHong ZhangJie YangBrent LinShih-Kai WangJung-Wook KimYong-Hee ChunJames P SimmerJan C-C Hu

Published in: Molecular genetics & genomic medicine (2019)

Ameloblastin is critical for the initiation of enamel ribbon formation, and its absence results in pathological mineralization within the enamel organ epithelia.

Keyphrases

high fat diet induced
type diabetes
metabolic syndrome
adipose tissue