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Effects of Vildagliptin and Metformin on Blood Pressure and Heart Rate Responses to Small Intestinal Glucose in Type 2 Diabetes.

Chinmay S MaratheLaurence G TrahairTanya J LittleMichelle J BoundXiang ZhangHang WuZilin SunMichael HorowitzChristopher K RaynerKaren L Jones
Published in: Diabetes care (2017)
Vildagliptin reduces BP and increases HR, whereas metformin increases HR without affecting BP during ID glucose infusion in type 2 diabetes. These distinct cardiovascular profiles during enteral nutrient exposure may have implications for postprandial hypotension.
Keyphrases
  • heart rate
  • type diabetes
  • blood pressure
  • blood glucose
  • glycemic control
  • heart rate variability
  • hypertensive patients
  • cardiovascular disease
  • insulin resistance
  • low dose