Comparative label-free proteomics of the neonatal meningitis-causing Escherichia coli K1 IHE3034 and RS218 morphotypes.

Nikola ZlatkovWilma GunnariUlrike Resch

Published in: Microbiology resource announcements (2024)

The proteome of two newborn meningitis Escherichia coli K1 (NMEC) morphotypes was examined via a label-free proteomics approach. Besides shared NMEC virulence factors, the two strains have different evolutionary strategies-strain IHE3034 tends to perform anaerobic respiration continuously, while strain RS218 maintains its filamentous morphotype due to active SOS response.

Keyphrases

label free
escherichia coli
cerebrospinal fluid
biofilm formation
microbial community
klebsiella pneumoniae
wastewater treatment
genome wide
gene expression
mass spectrometry
risk assessment
multidrug resistant
cystic fibrosis