Targeted delivery of ZNF416 siRNA-loaded liposomes attenuates experimental pulmonary fibrosis.

Demin ChengZiwei LiYue WangHaojie XiongWenqing SunSiyun ZhouYi LiuChunhui Ni

Published in: Journal of translational medicine (2022)

In this study, our results indicate that mechanosensitive ZNF416 is a potential molecular target for the treatment of pulmonary fibrosis. Strategies aimed at silencing ZNF416 could be a promising approach to fight against pulmonary fibrosis.

Keyphrases

pulmonary fibrosis
drug delivery
cancer therapy
risk assessment
human health
drug release
single molecule
combination therapy
hyaluronic acid
replacement therapy