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Clinical studies assessing the efficacy, effectiveness and safety of remdesivir in management of COVID-19: A scoping review.

Juan Pablo PimentelCassandra LaurieAnne CockcroftNeil Andersson
Published in: British journal of clinical pharmacology (2020)
Remdesivir might shorten the time to clinical improvement among hospitalized adults with severe COVID-19. Trial data report a similar proportion of adverse events in treated and control groups. The results of the 23 registered active trials, including more than 30 000 participants, will shed light on the efficacy and safety of the antiviral. The findings of the remaining clinical trials expected to report results in 2020 will allow a quantitative synthesis of available evidence.
Keyphrases
  • coronavirus disease
  • clinical trial
  • sars cov
  • phase ii
  • phase iii
  • study protocol
  • electronic health record
  • early onset
  • high resolution
  • big data
  • machine learning
  • mass spectrometry
  • placebo controlled