The 16-year experience in treating low-risk gestational trophoblastic neoplasia patients with failed primary methotrexate chemotherapy.

Xiaodong Wu Jiale Qin Tao Shen Weidong Fei Lili Chen Xing Xie Wei-Guo Lv

Published in: Journal of gynecologic oncology (2020)

Based on the good therapeutic effect and tolerable toxicity, we recommend Act-D salvage therapy for all patients with low-risk GTN who fail primary MTX chemotherapy. The higher serum hCG levels before Act-D salvage therapy may be associated with resistance to this treatment.

Keyphrases

locally advanced
weight gain
pregnant women
oxidative stress
high grade
squamous cell carcinoma
low dose
mesenchymal stem cells
rectal cancer
replacement therapy
preterm birth
smoking cessation
oxide nanoparticles