Visuospatial working memory in behavioural variant frontotemporal dementia: a comparative analysis with Alzheimer's disease using the box task.
David FoxeMuireann IrishJames CarrickSau Chi CheungHer TengJames R BurrellRoy P C KesselsOlivier PiguetPublished in: Journal of neurology (2024)
Our findings reveal significant visuospatial working memory impairments in bvFTD, albeit of lesser severity compared to disease-matched AD patients. The Box Task, a novel measure of visuospatial working memory, proved effective in differentiating between bvFTD and AD, outperforming many traditional neuropsychological measures. Overall, our findings highlight the utility of assessing visuospatial memory when differentiating between bvFTD and AD in the clinical setting.
Keyphrases
- working memory
- transcranial direct current stimulation
- attention deficit hyperactivity disorder
- end stage renal disease
- transcription factor
- newly diagnosed
- ejection fraction
- chronic kidney disease
- peritoneal dialysis
- binding protein
- prognostic factors
- contrast enhanced
- genome wide
- mild cognitive impairment
- gene expression
- magnetic resonance