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Severe metabolic acidosis due to massive metformin overdose in a man: a case report.

Aliasghar ManouchehriHale RashidianZakaria Zakariaei
Published in: Oxford medical case reports (2023)
Metformin-associated lactic acidosis is an extremely unusual but potentially life-threatening condition. This condition is typically observed in individuals who are suicidal or have type II diabetes mellitus (DM) and have taken an overdose of metformin. In this case, we present the instance of a 43-year-old man who had type II DM and was addicted to oral opium. Following a suicide attempt with an overdose of metformin, he experienced symptoms such as nausea, vomiting, weakness and lactic acidosis. However, prompt and effective treatment was administered, including hemodialysis and adequate hemodynamic resuscitation, leading to a successful outcome.
Keyphrases
  • cardiac arrest
  • chronic kidney disease
  • end stage renal disease
  • glycemic control
  • adipose tissue
  • peritoneal dialysis
  • early onset
  • type diabetes
  • skeletal muscle
  • weight loss
  • cardiopulmonary resuscitation
  • sleep quality