The diagnostic and prognostic utility of oxidative stress circulatory biomarkers in traumatic brain injury patients: a systematic review.
Jake Michael McDonnellKielan WilsonAndrew R StevensDavid J DaviesAntonio BelliPhilip J O'HalloranPublished in: Brain injury (2024)
The care for patients with TBI remains a complex clinical challenge with a high morbidity and mortality profile. Evidenced by this review, circulatory OSMxs appear to have the potential to supplement current diagnostic measures, in addition to identifying new treatment strategies and monitoring recovery. Despite early promise, the evidence for such markers remains in its infancy and robust prospective studies are needed.
Keyphrases
- traumatic brain injury
- oxidative stress
- end stage renal disease
- ejection fraction
- newly diagnosed
- healthcare
- chronic kidney disease
- extracorporeal membrane oxygenation
- palliative care
- severe traumatic brain injury
- dna damage
- ischemia reperfusion injury
- machine learning
- patient reported outcomes
- induced apoptosis
- pain management
- deep learning
- chronic pain
- weight loss
- diabetic rats