Selenium-Containing Amino Acids Protect Dextran Sulfate Sodium-Induced Colitis via Ameliorating Oxidative Stress and Intestinal Inflammation.

Chengxin ShiFengli YueFeiyu ShiQian QinLizhao WangGuanghui WangLijun MuDan LiuYaguang LiTianyu YuJunjun She

Published in: Journal of inflammation research (2021)

We found that selenocysteine and selenocystine ameliorated DSS-induced IBD via reducing oxidative stress and intestinal inflammation, indicating that selenium-containing amino acids could be a novel therapeutic option for patients with IBD.

Keyphrases

oxidative stress
diabetic rats
amino acid
dna damage
ischemia reperfusion injury
induced apoptosis
high glucose
ulcerative colitis
drug induced
heat shock
signaling pathway