Recombinant antithrombin attenuates acute kidney injury associated with rhabdomyolysis: an in vivo animal study.

Tomotaka MiuraTomoki OkudaKodai SuzukiHideshi OkadaHiroyuki TomitaChihiro TakadaKosuke MoriHirotaka AsanoSoichiro KanoYugo WakayamaYohei FukudaHirotsugu FukudaAyane NishioYuki KawasakiAyumi KurodaKeiko SuzukiRyo KamidaniHaruka OkamotoTetsuya FukutaYuichiro KitagawaTakahito MiyakeKeita NakaneAkio SuzukiTakahiro YoshidaNobuyuki TetsukaShozo YoshidaTakuya KoieShinji Ogura

Published in: Intensive care medicine experimental (2024)

Treatment with rAT suppressed rhabdomyolysis-induced AKI, suggesting that rAT therapy may be a novel therapeutic approach.

Keyphrases

acute kidney injury
cardiac surgery
oxidative stress
diabetic rats
high glucose
endothelial cells
combination therapy
mesenchymal stem cells
smoking cessation