MALDI-TOF mass spectrometry as a diagnostic tool in human and veterinary helminthology: a systematic review.
Maureen FeucherollesSven PoppertJürg UtzingerSören Leif BeckerPublished in: Parasites & vectors (2019)
Data on the use of MALDI-TOF MS for the diagnosis of helminths are scarce, but recent evidence suggests a potential role for a reliable identification of nematodes. Future research should explore the diagnostic accuracy of MALDI-TOF MS for identification of (i) adult helminths, larvae and eggs shed in faecal samples; and (ii) helminth-related proteins that are detectable in serum or body fluids of infected individuals.
Keyphrases
- mass spectrometry
- liquid chromatography
- gas chromatography
- high performance liquid chromatography
- capillary electrophoresis
- endothelial cells
- high resolution
- bioinformatics analysis
- electronic health record
- current status
- tandem mass spectrometry
- induced pluripotent stem cells
- young adults
- zika virus
- aedes aegypti
- deep learning
- solid phase extraction
- drosophila melanogaster
- drug induced