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Lichen planus pemphigoides: A unique form of bullous and lichenoid eruptions secondary to nivolumab.

Rohan R ShahChinmoy BhateAmanda HernandezChin Hung Ho
Published in: Dermatologic therapy (2022)
The widespread use of PD-1 inhibitors to treat various solid tumors has brought certain challenges for the clinician, including immune-related adverse events (irAEs). Cutaneous toxicities are among the most observed irAEs. Bullous and lichenoid dermatoses following PD-1 inhibitor therapy have been described. Here we report a novel case of lichen planus pemphigoides, featuring characteristics of both bullous pemphigoid and lichen planus, in a patient treated with nivolumab for renal cell carcinoma. We subsequently review all three cutaneous conditions which may arise in the context of PD-1 inhibitor therapy.
Keyphrases
  • renal cell carcinoma
  • case report
  • mesenchymal stem cells
  • bone marrow
  • newly diagnosed
  • replacement therapy