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Clinical and subclinical acute kidney injury in children with mild-to-moderate COVID-19.

Seha Kamil SaygiliNur CanpolatRumeysa Yasemin CicekAyse AgbasEsra Karabag YilmazAyse Ayzit Kilinc SakalliDeniz AygunGülsen AkkocKaan Can DemirbaşDildar KonukogluHaluk CokugrasSalim CaliskanLale Sever
Published in: Pediatric research (2022)
The key message of our article is that not only children with severe disease but also children with mild or moderate disease have an increased risk for kidney injury due to COVID-19. Urinary biomarkers enable the diagnosis of a significant number of patients with subclinical AKI in patients without elevation in serum creatinine. Our findings reveal that patients with high neutrophil count may be more prone to develop AKI and should be followed up carefully. We conclude that even children with mild or moderate COVID-19 disease courses should be evaluated for AKI and subclinical AKI, which may improve patient outcomes.
Keyphrases
  • acute kidney injury
  • coronavirus disease
  • sars cov
  • young adults
  • end stage renal disease
  • gene expression
  • chronic kidney disease
  • high intensity
  • dna methylation
  • prognostic factors
  • peripheral blood