Thermal Stability and in Vitro Elution Kinetics of Alternative Antibiotics in Polymethylmethacrylate (PMMA) Bone Cement.
Ashley E LevackKathleen TurajaneXu YangAndy O MillerAlberto V CarliMathias P G BostromDavid S WellmanPublished in: The Journal of bone and joint surgery. American volume (2021)
Amikacin and meropenem show pharmacologic promise as potential acceptable alternatives for local delivery in PMMA for treatment of orthopaedic infections. Further work to establish clinical relevance and utility is needed.