SARS-CoV-2 spike protein S1 activates Cx43 hemichannels and disturbs intracellular Ca 2+ dynamics.

Juan Prieto-VillalobosClaudia M LuceroMaximiliano RovegnoGonzalo I GómezMauricio A RetamalJuan Andrés Orellana

Published in: Biological research (2023)

We hypothesize that Cx43 hemichannels could represent potential pharmacological targets for developing therapies to counteract SARS-CoV-2 infection and their long-term consequences.

Keyphrases

sars cov
respiratory syndrome coronavirus
protein protein
coronavirus disease
reactive oxygen species
amino acid
protein kinase
climate change