Loss of DIP2C in RKO cells stimulates changes in DNA methylation and epithelial-mesenchymal transition.

Chatarina LarssonMuhammad Akhtar AliTatjana PandzicAnders M LindrothLiqun HeTobias Sjöblom

Published in: BMC cancer (2017)

Loss of DIP2C triggers substantial DNA methylation and gene expression changes, cellular senescence and epithelial-mesenchymal transition in cancer cells.

Keyphrases

dna methylation
epithelial mesenchymal transition
gene expression
induced apoptosis
genome wide
transforming growth factor
signaling pathway
cell cycle arrest
dna damage
endothelial cells
copy number
oxidative stress
stress induced