A BODIPY-based fluorescent sensor for the detection of Pt2+ and Pt drugs.
Fung-Kit TangJiaqian ZhuFred Ka-Wai KongMaggie NgQingyuan BianVivian Wing-Wah YamAnfernee Kai-Wing TseYu-Chung TseKen Cham-Fai LeungPublished in: Chemical communications (Cambridge, England) (2020)
A BODIPY-based fluorescent sensor PS with an NO4S2 podand ligand was studied for the selective detection of Pt2+ over 21 cations as well as selected platinum drugs in aqueous medium. The platinum sensor PS shows 28-fold, 22-fold and 14-fold fluorescence turn-on enhancements to Pt2+, cisplatin and nedaplatin, and was thereby employed to detect platinum drugs in A-549 human lung cancer cells.