Towards Accurate and Precise Image-Guided Radiotherapy: Clinical Applications of the MR-Linac.
James W RandallNikhil RammohanIndra J DasPoonam YadavPublished in: Journal of clinical medicine (2022)
Advances in image-guided radiotherapy have brought about improved oncologic outcomes and reduced toxicity. The next generation of image guidance in the form of magnetic resonance imaging (MRI) will improve visualization of tumors and make radiation treatment adaptation possible. In this review, we discuss the role that MRI plays in radiotherapy, with a focus on the integration of MRI with the linear accelerator. The MR linear accelerator (MR-Linac) will provide real-time imaging, help assess motion management, and provide online adaptive therapy. Potential advantages and the current state of these MR-Linacs are highlighted, with a discussion of six different clinical scenarios, leading into a discussion on the future role of these machines in clinical workflows.
Keyphrases
- contrast enhanced
- magnetic resonance imaging
- early stage
- magnetic resonance
- computed tomography
- diffusion weighted imaging
- locally advanced
- radiation induced
- radiation therapy
- high resolution
- rectal cancer
- climate change
- oxidative stress
- type diabetes
- healthcare
- social media
- prostate cancer
- robot assisted
- mesenchymal stem cells
- bone marrow
- current status
- insulin resistance
- photodynamic therapy
- fluorescence imaging
- minimally invasive