Exposure to intravenous posaconazole in critically ill patients with influenza: A pharmacokinetic analysis of the POSA-FLU study.
Ruth Van DaeleJoost WautersErwin DreesenJerina BoelensEric NulensPiet LormansLore VanderbekeCato JacobsBart J A RijndersPaul E VerweijRoger J M BrüggemannIsabel SprietPublished in: Mycoses (2022)
Our analysis indicates that posaconazole may be a suitable drug to further investigate for prophylaxis, as TA for prophylaxis was reached. Exposure targets for treatment were insufficiently attained in this population.