Vitamin D increases remyelination by promoting oligodendrocyte lineage differentiation.

Ulises Gómez-PinedoJesús Adriel CuevasMaría Soledad Benito-MartínLidia Moreno-JiménezNoelia Esteban-GarciaLaura Torre-Fuentes Jordi A Matias-Guiu Vanesa PytelPaloma MonteroJorge Matias-Guiu

Published in: Brain and behavior (2019)

Our results support the hypothesis that regardless of the presence of VitD deficiency, treatment with VitD may contribute to remyelination by promoting the proliferation of oligodendrocyte precursor cells.

Keyphrases

induced apoptosis
signaling pathway
cell cycle arrest
replacement therapy
endoplasmic reticulum stress
cell proliferation