Characterization of the metabolites of tirabrutinib generated from rat, dog and human liver microsomes using ultra-high-performance liquid chromatography combined with high-resolution mass spectrometry.
Hongjian ZhangZhen HuHuiping ZhangXiyan SunJianming YangJie YuanPublished in: Rapid communications in mass spectrometry : RCM (2022)
This study provides valuable data regarding the in vitro metabolism of tirabrutinib, which may be helpful for further safety assessment of this drug.