Steroid therapy in acute exacerbation of fibrotic interstitial lung disease.
Kavya KoshyHayley BarnesErica FarrandIan N GlaspolePublished in: Respirology (Carlton, Vic.) (2024)
In this two-centre retrospective study of 107 patients, AE-FILD demonstrates a high risk of mortality, at a level similar to that seen for AE-IPF, despite steroid treatment. Clinicians should consider other precipitating factors for exacerbations and use steroids judiciously. Further prospective trials are needed to determine the role of corticosteroids in AE-FILD.
Keyphrases
- interstitial lung disease
- idiopathic pulmonary fibrosis
- systemic sclerosis
- chronic obstructive pulmonary disease
- end stage renal disease
- ejection fraction
- newly diagnosed
- rheumatoid arthritis
- prognostic factors
- respiratory failure
- cardiovascular events
- peritoneal dialysis
- palliative care
- type diabetes
- risk factors
- stem cells
- drug induced
- mesenchymal stem cells
- cell therapy
- extracorporeal membrane oxygenation
- aortic dissection