Nonpreferential but Detrimental Accumulation of Macrophages With Clonal Hematopoiesis-Driver Mutations in Cardiovascular Tissues-Brief Report.
Tsai-Sang DederichsAssel YerdenovaHauke HorstmannTamara Antonela VicoSimone NüblingRémi PeyronnetDietmar PfeiferConstantin von Zur MuehlenTimo HeidtDennis WolfMartin CzernyDirk WestermannIngo HilgendorfPublished in: Arteriosclerosis, thrombosis, and vascular biology (2024)
Quantitatively, CHIP-mutated myeloid cells did not preferentially accumulate in cardiovascular tissues, but qualitatively, they expressed a more disease-prone phenotype.