Interpreting ambiguous 'trace' results in Schistosoma mansoni CCA Tests: Estimating sensitivity and specificity of ambiguous results with no gold standard.

Michelle N ClementsChristl A DonnellyAlan FenwickNarcis B KabatereineSarah C L KnowlesAboulaye MeitéEliézer K N'GoranYolisa NaluleSarah NogaroAnna E PhillipsEdridah Muheki TukahebwaFiona M Fleming

Published in: PLoS neglected tropical diseases (2017)

Incorporation of ambiguous results into an LCA enables the effect of different treatment thresholds to be directly assessed and is applicable in many fields. Our results showed that CCA with trace as positive most accurately estimated infection prevalence.

Keyphrases

heavy metals
risk factors
structural basis
replacement therapy