MTA-induced Notch activation enhances the proliferation of human dental pulp cells by inhibiting autophagic flux.

Published in: International endodontic journal (2017)

MTA extract promoted the proliferation of hDPCs in part by activating Notch signalling through inhibition of autophagic flux during the early stage and, thus, might potentially induce rapid restoration of injured pulps.

Keyphrases

signaling pathway
induced apoptosis
cell death
early stage
cell cycle arrest
endothelial cells
pi k akt
high glucose
cell proliferation
oxidative stress
diabetic rats
induced pluripotent stem cells
drug induced
squamous cell carcinoma
anti inflammatory
endoplasmic reticulum stress
lymph node