Nicotinamide N -methyltransferase promotes M2 macrophage polarization by IL6 and MDSC conversion by GM-CSF in gallbladder carcinoma.

Yang Li Bo Yang Huijie Miao Liguo Liu Ziyi Wang Chengkai Jiang Yang Yang Shimei Qiu Xuechuan Li Yajun Geng Yijian Zhang Ying-Bin Liu

Published in: Hepatology (Baltimore, Md.) (2023)

These data highlight the critical role of NNMT in GBC progression. Inhibition of NNMT by JBSNF-000088 is a potential molecular target for GBC immunotherapy.

Keyphrases

electronic health record
big data
human health
risk assessment
cerebrospinal fluid
climate change