FLT3, a prognostic biomarker for acute myeloid leukemia (AML): Quantitative monitoring with a simple anti-FLT3 interaction and flow cytometric method.

Chadarat AmpasavateWasimon JutapakdeeRungsinee PhongpradistSingkome TimaAdisak TantiworawitPimlak CharoenkwanDujrudee ChinwongSongyot Anuchapreeda

Published in: Journal of clinical laboratory analysis (2019)

The effective, reliable, rapid, and economical analytical technique using the developed flow cytometric method was demonstrated for FLT3 protein determination on leukemic cell surface. This method provided a practical analysis of FLT-3 biomarker levels which is valuable for physician decision in acute leukemia treatment.

Keyphrases

acute myeloid leukemia
allogeneic hematopoietic stem cell transplantation
cell surface
primary care
high resolution
small molecule
protein protein
decision making
binding protein
simultaneous determination