Cardiopulmonary exercise testing and the 2022 definition of pulmonary hypertension.

Parameters of cardiopulmonary exercise testing significantly discriminate between healthy subjects and patients with pulmonary hypertension (PH), also according to the new 2022 definition of pulmonary hypertension (mean pulmonary arterial pressure mPAP > 20 mmHg). The cut-offs indicating on PH were peakVO 2  ≤ 16.7 mL/min/kg (Youden-Index YI = 0.79), p et CO 2 @AT ≤ 34 mmHg (YI = 0.67), and VE/VCO 2 @AT ≤ 30 (YI = 0.76).