The Role of Molecular Imaging in a Muscle-Invasive Bladder Cancer Patient: A Narrative Review in the Era of Multimodality Treatment.
Vincenzo CuccurulloGiuseppe Danilo Di StasioFrancesco MantiPierpaolo ArcuriRocco DamianoGiuseppe Lucio CasciniPublished in: Diagnostics (Basel, Switzerland) (2021)
Diagnostic imaging in bladder cancer plays an important role since it is needed from pretreatment staging to follow-up, but a morphological evaluation performed with both CT and MRI showed low sensitivities and specificities in detecting pathologic lymph nodes, due to the occurrence of false positive results. Implementation of functional information provided by PET/CT could be a determinant in the management of patients with muscle-invasive bladder cancer. A focus on the role of 18F-FDG PET/CT and alternative tracers in patients with muscle-invasive bladder cancer is provided in this analysis in order to outline its potential applications in staging settings and response evaluation after neoadjuvant chemotherapy.
Keyphrases
- muscle invasive bladder cancer
- neoadjuvant chemotherapy
- lymph node
- pet ct
- sentinel lymph node
- locally advanced
- positron emission tomography
- contrast enhanced
- primary care
- magnetic resonance imaging
- healthcare
- risk assessment
- computed tomography
- case report
- diffusion weighted imaging
- squamous cell carcinoma
- radiation therapy
- combination therapy
- magnetic resonance
- social media
- dual energy
- replacement therapy
- fluorescence imaging