Risk of Pregnancy Termination and Congenital Anomalies After Domperidone Exposure: A Study in the EFEMERIS Database.

Mélanie AraujoClémentine VabreJustine BeneventAgnès SommetChristine Damase-MichelCaroline Hurault-DelarueIsabelle Lacroix

Published in: Drug safety (2021)

This is the first comparative study to enrol a large number of pregnant women exposed to domperidone. Data regarding the malformation rate following exposure to domperidone during the first trimester of pregnancy are reassuring. Women exposed to domperidone during pregnancy have a decreased risk for natural pregnancy termination, probably owing to an indication bias.

Keyphrases

pregnancy outcomes
pregnant women
preterm birth
electronic health record
emergency department
adipose tissue
skeletal muscle
artificial intelligence
metabolic syndrome