[Risk of post-thrombotic syndrome following direct oral anticoagulant intake: a systematic review and meta-analysis].
Kirill V LobastovIlya SchastlivtsevA B BargandzhiyaPublished in: Khirurgiia (2022)
Moderate quality evidence suggests that DOACs are associated with significant less risk of any PTS and severe PTS compared to VKA in patients with deep vein thrombosis. Among all DOACs, only rivaroxaban has clear data confirming PTS risk reduction. The use of flavonoids in adjunction to rivaroxaban can further improve treatment outcomes.