Oncolytic Virus Senecavirus A Inhibits Hepatocellular Carcinoma Proliferation and Growth by Inducing Cell Cycle Arrest and Apoptosis.

Tao GongXiao LiuQingyuan LiDonald R BranchMelika LoriaminiWenxian WenYaoqiang ShiQi TanBin FanZhonghui ZhouYujia LiChunhui YangShilin LiXiaoqiong Duan Limin Chen

Published in: Journal of clinical and translational hepatology (2024)

SVA inhibits the growth of HCC cells by inducing cell cycle arrest and apoptosis. It does not cause any noticeable toxicity to vital organs.

Keyphrases

cell cycle arrest
cell death
pi k akt
signaling pathway
cell proliferation
induced apoptosis
endoplasmic reticulum stress