High glucose mediates apoptosis and osteogenesis of MSCs via downregulation of AKT-Sirt1-TWIST.
Wenxia RenMiaomiao ChaiMingli JiangYan ZhouWensong TanPublished in: Molecular biology reports (2022)
Our data demonstrates that high glucose induces MSC apoptosis and enhances osteogenesis differentiation via downregulation of AKT-Sirt1-TWIST.