Postoperative complications with neuromuscular blocking drugs and/or reversal agents in obstructive sleep apnea patients: a systematic review.
Khawaja Rashid HafeezArvind TutejaMandeep SinghDavid T WongMahesh NagappaFrances ChungJean WongPublished in: BMC anesthesiology (2018)
OSA patients who receive intraoperative NMBD may be at higher risk for postoperative hypoxemia, respiratory failure and residual neuromuscular blockade compared to non-OSA patients. There is some, albeit very limited evidence that NMBD reversal with sugammadex may be associated with less PPCs than neostigmine in patients with OSA. More high-quality studies are needed.
Keyphrases
- obstructive sleep apnea
- end stage renal disease
- newly diagnosed
- ejection fraction
- chronic kidney disease
- positive airway pressure
- peritoneal dialysis
- prognostic factors
- respiratory failure
- patients undergoing
- extracorporeal membrane oxygenation
- patient reported outcomes
- intensive care unit
- mechanical ventilation