Proof of Principle of Combining Fluorescence-Guided Surgery with Photoimmunotherapy to Improve the Outcome of Pancreatic Cancer Therapy in an Orthotopic Mouse Model.

Hiroto NishinoMichael A TurnerSiamak AmirfakhriThinzar M LwinMojgan HosseiniBernhard B SingerRobert M HoffmanMichael Bouvet

Published in: Annals of surgical oncology (2022)

FGS and adjuvant PIT can be combined by using a single antibody-fluorophore conjugate to significantly reduce the frequency of pancreatic cancer recurrence.

Keyphrases

cancer therapy
mouse model
drug delivery
minimally invasive
coronary artery bypass
early stage
single molecule
fluorescent probe
free survival
surgical site infection
energy transfer