Circulating micro-RNAs differentially expressed in Korean Alzheimer's patients with brain A accumulation activate amyloidogenesis.

Sakulrat MankhongSujin KimSohee MoonSeong-Hye ChoiHyo-Bum KwakDong-Ho ParkPratik ShahPhil Hyu LeeSeong Wook YangJu-Hee Kang

Published in: The journals of gerontology. Series A, Biological sciences and medical sciences (2022)

In conclusion, despite of the limited diagnostic utility of selected miRNAs as plasma or plasma EV biomarkers, the discovered miRNAs may play a role in amyloidogenesis during AD onset and progression.

Keyphrases

cognitive decline
white matter
multiple sclerosis
cerebral ischemia
mild cognitive impairment
brain injury
blood brain barrier