Can Antinuclear Antibodies (ANA) be Monoclonal?

Laura BiedermanAnjali A SatoskarMohankumar DoraiswamySamir ParikhBrad RovinBrian MussioGalina MikhalinaSergey V Brodsky

Published in: Case reports in nephrology (2021)

We identified a new unique pattern of nuclear stain by immunofluorescence in kidney biopsies that suggests the presence of monoclonal ANA. Workup for underlying monoclonal gammopathy is warranted in such patients.

Keyphrases

end stage renal disease
multiple myeloma
ejection fraction
chronic kidney disease
prognostic factors
peritoneal dialysis
patient reported outcomes