DNA Methylation and Protein Markers of Chronic Inflammation and Their Associations With Brain and Cognitive Aging.
Eleanor L S ConoleAnna J StevensonSusana Muñoz ManiegaSarah E HarrisClaire GreenMaria Del Carmen Valdés-HernándezMathew A HarrisMark E BastinJoanna Marguerite WardlawIan J DearyVeronique E MironHeather C WhalleyRiccardo E MarioniSimon R CoxPublished in: Neurology (2021)
This study provides Class II evidence that a DNAm signature of CRP levels is more strongly associated with brain health outcomes than serum CRP levels.